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doi:10.1016/j.jhep.2018.09.021 Hall EW, Weng MK, Harris AM, et al

Barrier-Stressed Skin

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Changes in immune cells include dermal neutrophil, lymphocyte, and monocyte infiltration, leading to changes in inflammatory cytokines, such as increasing the amount of tumor necrosis factor-α (TNF-α) and the pro-inflammatory cytokine IL-1 in the entire human skin tissue, and decreasing the expression of the anti-inflammatory cytokine IL-10 (111)

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