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270 In an inflammatory response, activation of epithelial and immune cells triggers NOXs to generate ROS, which can directly kill microorganisms
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Keywords: Ulcerative colitis (UC), Genetic predisposition, Immune dysregulation, Alteration of intestinal flora, Biologic therapy, Herbal treatment Introduction Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that manifests with inflammation and ulcers in the colonic lining, resulting in a spectrum of symptoms including abdominal pain, diarrhea, rectal bleeding, tenesmus (a sense of pressure), and weight loss [1, 2]
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